matrin-3 (MATR3, KIAA0723 matrin)

Function

• may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network
• in association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs
• part of complex consisting of SFPQ, NONO & MATR3

Structure

• contains 1 matrin-type Zn+2 finger
• contains 2 RRM domain (RNA recognition motifs)

Compartment

nucleus matrix

More general terms

• nuclear protein
• RNA-binding protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9782
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9782
• OMIM: https://mirror.omim.org/entry/164015
• UniProt: http://www.uniprot.org/uniprot/P43243.html