bromodomain-containing protein 2; protein RING3; O27.1.1 (BRD2, KIAA9001, RING3)

Function

• may play a role in spermatogenesis or folliculogenesis
• interacts with E2F1 & with histone H4 acetylated at Lys-13

Structure

• homodimer
• one bromodomain is sufficient for a partial interaction with histone H4 acetylated at Lys-13
• contains 2 bromo domains
• contains 1 ET domain

Compartment

nucleus (putative)

Alternative splicing

named isoforms=2

More general terms

• nuclear protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P25440.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6046
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6046
• OMIM: https://mirror.omim.org/entry/601540