DNA-binding protein inhibitor ID-1; inhibitor of DNA binding 1 (ID1)

Function

• ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding
• heterodimer with other HLH proteins
• interacts with COPS5

Structure

contains 1 basic helix-loop-helix (bHLH) domain

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

• expression correlates with proliferation in some types of cells

More general terms

• DNA-binding protein inhibitor; inhibitor of DNA binding (ID)

Database

• UniProt: http://www.uniprot.org/uniprot/P41134.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3397
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3397
• OMIM: https://mirror.omim.org/entry/600349