retinol-binding protein 3; interphotoreceptor retinoid-binding protein; IRBP; interstitial retinol-binding protein (RBP3)

Function

• IRBP shuttles 11-cis & all trans retinoids between the retinol isomerase in the pigment epithelium & the visual pigments in the retinal photoreceptor cells

Structure

belongs to the peptidase S41A family

Compartment

• secreted into the interphotoreceptor matrix permeating the space between the retina & contiguous layer of pigment epithelium

Notes

• uncertain whether Met-1 or Met-2 is the initiator

More general terms

• secreted protein
• retinol binding protein
• lipocalin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5949
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5949
• OMIM: https://mirror.omim.org/entry/180290
• UniProt: http://www.uniprot.org/uniprot/P10745.html