CD179a; immunoglobulin iota chain; CD179 antigen-like family member A; protein VpreB1; V(pre)B protein; VpreB protein (VPREB1, VPREB)

Function

• associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells
• this complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation
• associates non-covalently with IGLL1

Structure

• belongs to the immunoglobulin superfamily
• contains 1 Ig-like V-type domain

Expression

only expressed by pre-B-cells

Laboratory

• CD179a blasts in specimen
  • cytoplasmic CD179a blasts in specimen
• CD179a blasts in blood
  • cytoplasmic CD179a blasts in blood
• CD179a blasts in bone marrow
  • cytoplasmic CD179a blasts in bone marrow

More general terms

• protein subunit
• CD antigen

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7441
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7441
• OMIM: https://mirror.omim.org/entry/605141
• UniProt: http://www.uniprot.org/uniprot/P12018.html