dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; oligosaccharyl transferase subunit DAD1; defender against cell death 1; DAD-1 (DAD1)

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Introduction

Subunit of oligosaccharyltransferase complex that inititates N-glycosylation. Also plays anti-apoptotic role during development. Homozygous mutants die in utero.

Function

Structure

belongs to the DAD/OST2 family

Compartment

membrane (putative)

More general terms

References

  1. UniProt http://www.uniprot.org/uniprot/P46966.html
  2. Rampon C, Jiang CH, Dong H, Tang YP, Lockhart DJ, Schultz PG, Tsien JZ, Hu Y. Effects of environmental enrichment on gene expression in the brain. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12880-4. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11070096
  3. NIEHS-SNPs http://egp.gs.washington.edu/data/dad1/

Database