alpha-fodrin; spectrin alpha chain, brain; spectrin, non-erythroid alpha chain; alpha-II spectrin; fodrin alpha chain (SPTAN1, SPTA2)

Function

• interacts with isoform 1 of ACP1
• interacts with calmodulin (CALM)

Structure

• belongs to the spectrin family
• contains 3 EF-hand domains
• contains 1 SH3 domain
• contains 23 spectrin repeats

Compartment

• cytoplasm, cytoskeleton. cytoplasm, cell cortex

Alternative splicing

named isoforms=3

More general terms

• protein subunit

Component of

• fodrin (non erythrocytic spectrin)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6709
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6709
• OMIM: https://mirror.omim.org/entry/182810
• UniProt: http://www.uniprot.org/uniprot/Q13813.html