THO complex subunit 3 (Tho3, TEX1 homolog, THOC3)

Function

• component of THO/TREX complex
• may physically link proteins that function in transcription & in RNA export

Structure

contains 6 WD repeats

Compartment

nucleus (probable)

Genetics

• there are two almost identical copies of this gene on chromosome 5q35
• one copy is frameshifted & unlikely to encode a functional protein

More general terms

• protein subunit
• WD repeat protein family

Component of

• THO/TREX complex

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8432
• OMIM: https://mirror.omim.org/entry/606929
• UniProt: http://www.uniprot.org/uniprot/Q96J01.html