dynactin subunit 3 (dynactin complex subunit 22 kD subunit, p22, DCTN3, DCNT22)

Function

• subunit of dynactin

Structure

belongs to the dynactin subunit 3 family

Compartment

• cytoplasm, centrosome, kinetochore, spindle
• localizes to punctate cytoplasmic structures & to the centrosome during interphase, & to kinetochores & to spindle poles throughout mitosis
• colocalizes with dynein to the cleavage furrow & to midbody of dividing cells

Alternative splicing

named isoforms=4

Expression

• ubiquitously expressed, muscle & pancreas > brain

More general terms

• protein subunit

Component of

• dynactin

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1125
• OMIM: https://mirror.omim.org/entry/607387
• UniProt: http://www.uniprot.org/uniprot/O75935.html