granular cast

Introduction

See urinary cast

• a brown granular cast may also be a muddy brown cast

Etiology

• renal tubular disease (acute tubular necrosis)
• tubulointerstitial disease
• renal glomerular disease
  • medication-induced decrease in glomerular perfusion
    • triple whammy of NSAID, ACE inhibitor & diuretic with volume depletion decreases glomerular perfusion
• renal allograft rejection
• pyelonephritis
• viral infections
• chronic lead poisoning
• hematuria
• renal papillary necrosis

Epidemiology

• common

More general terms

• urinary cast

More specific terms

• coarse granular cast
• fine granular cast