sputum cytology
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Reference interval
- normal epithelial cells
Clinical significance
- tumors within the pulmonary system frequently slough cells into respiratory secretions
- when sputum is collected, malignant cells may be seen with
- squamous cell carcinoma (60%)
- small cell carcinoma (21%)
- adenocarcinoma (16%)
- large cell carcinoma (13%)
- bronchoscopy & percutaneous lung biopsy have largely replaced sputum cytology[2]*
- used mostly for patients with productive cough, abnormal chest X-ray & negative bronchoscopy
- less sensitive than chest X-ray for detection of lung cancer
* MKSAP19 refers to blood-tinged sputum as hemoptysis worked-up with contrast-enhanced chest CT[3]
More general terms
Additional terms
References
- ↑ Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 769
- ↑ Jump up to: 2.0 2.1 Mosby's Diagnostic and Laboratory Test Reference, 9th edition, Pagana DS and Pagana TJ editors, Mosby, Elsevier, St. Louis, 2009, pg 876
- ↑ Jump up to: 3.0 3.1 Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022