thioredoxin-interacting protein (vitamin D3 up-regulated protein 1, thioredoxin-binding protein 2, TXNIP, VDUP1)

Function

• may mediate/modulate oxidative stress by inhibiting thioredoxin activity
• interacts with TXN/thioredoxin through its redox-active site

Structure

• belongs to the arrestin family

Compartment

cytoplasm

Expression

induced by 1,25-dihydroxyvitamin D3

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/606599
• UniProt: http://www.uniprot.org/uniprot/Q9H3M7.html