progesterone-induced-blocking factor 1 (PIBF1, C13orf24, PIBF)
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Function
- mediator of progesterone
- interacts with phospholipase A2
- interferes with arachidonic acid metabolism
- induces a Th2 biased immune response
- role in NK activity
- anti-abortive effect
Alternative splicing
named isoforms=3
Expression
- expressed testis > spleen, thymus, prostate, ovary, small intestine, colon
- induced by progesterone