cardiotrophin-1 (CT-1, CTF1)

Function

• induces cardiac myocyte hypertrophy in vitro
• binds to & activates the ILST/gp130 receptor

Structure

• belongs to the IL-6 superfamily

Compartment

secreted

Expression

• expressed in heart, skeletal muscle, prostate, ovary > lung, kidney, pancreas, thymus, testis and small intestine
• little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/600435
• UniProt: http://www.uniprot.org/uniprot/Q16619.html