protein FRG1 (facioscapulohumeral muscular dystrophy region gene 1 protein, FSHD region gene 1 protein, FRG1)

Function

• role in processing of pre-rRNA or in assembly of rRNA into ribosomal subunits (putative)
• role in pre-mRNA splicing (putative)
• component of spliceosome C complex

Compartment

• nucleus, Cajal body, nuclear speckle, nucleolus
• 1st expressed in Cajal bodies & nuclear speckles
• as speckle expression diminishes, expression is seen in dense structures (dense fibrillar component & granular component) of nucleolus

Expression

• expressed in adult muscle, lymphocytes, fetal brain, muscle, placenta

More general terms

• other protein

Component of

• spliceosome C complex

Database

• OMIM: https://mirror.omim.org/entry/601278
• UniProt: http://www.uniprot.org/uniprot/Q14331.html