cingulin (CGN, KIAA1319)

Function

• formation & regulation of tight junction paracellular permeability barrier
• interacts with TJP1/ZO-1

Structure

• homodimer

Compartment

• cytoplasmic face of tight junctions of polarized epithelia & some endothelia

Expression

• expressed in pancreas, kidney, liver, lung
• not expressed in skeletal muscle, placenta, brain, heart

More general terms

• other protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9P2M7.html