checkpoint protein HUS1

Function

• component of the 9-1-1 cell-cycle checkpoint response complex
• does not interact with RAD17

Compartment

• nucleus, cytoplasm
• in discrete nuclear foci upon DNA damage
• localized also in cytoplasm
• DNA damage induces its nuclear translocation
• shuttles between the nucleus & the cytoplasm

Expression

ubiquitous

More general terms

• other protein

Component of

• 9-1-1 cell-cycle checkpoint response complex

Database

• OMIM: https://mirror.omim.org/entry/603760
• UniProt: http://www.uniprot.org/uniprot/O60921.html