von Willebrand factor A domain-containing protein 5A; breast cancer suppressor candidate 1; BCSC-1; loss of heterozygosity 11 chromosomal region 2 gene A protein (VWA5A, BCSC1, LOH11CR2A)

Function

• may play a role in tumorigenesis as a tumor suppressor
• altered expression & disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis

Structure

• contains 1 VIT domain
• contains 1 VWFA domain

Alternative splicing

named isoforms=4

Expression

• expressed at low level in many tissues
• not expressed in 80% of tumor cell lines tested

More general terms

• other protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4013
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4013
• OMIM: https://mirror.omim.org/entry/602929
• UniProt: http://www.uniprot.org/uniprot/O00534.html