protein AF-9; ALL1 fused gene from chromosome 9 protein; myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; YEATS domain-containing protein 3 (MLLT3, AF9, YEATS3)

Function

• interacts with BCOR
• interacts with CBX8

Structure

contains 1 YEATS domain

Compartment

nucleus (putative)

Pathology

• chromosomal translocation t(9;11)(p22;q23) involving MLLT3 with MLL/HRX is associated with acute leukemias; the result is a rogue activator protein

More general terms

• nuclear protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P42568.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4300
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4300
• OMIM: https://mirror.omim.org/entry/159558