SCL-interrupting locus protein

From Aaushi
Jump to navigation Jump to search

Introduction

Fusion protein with SCL protein seen in 1;14 translocations of hematopoietic stem cell leukemias.

More general terms

References

  1. Aplan PD, Lombardi DP, Ginsberg AM, Cossman J, Bertness VL, Kirsch IR. Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity. Science. 1990 Dec 7;250(4986):1426-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2255914