serine/threonine protein kinase 33 (STK33)

Structure

• belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily
• contains 1 protein kinase domain

Compartment

cytoplasm, perinuclear region

Alternative splicing

named isoforms=2

Expression

• expressed in testis, fetal lung heart > pituitary gland, kidney, interventricular septum, pancreas, heart, trachea, thyroid gland, uterus
• NOT expressed in nervous system

Pathology

• KRAS-dependent tumor cells are dependent upon activity of STK33

More general terms

• serine/threonine kinase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=65975
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:65975
• OMIM: https://mirror.omim.org/entry/607670
• UniProt: http://www.uniprot.org/uniprot/Q9BYT3.html