aspartyl aminopeptidase (DNPEP)
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Function
- role in intracellular protein & peptide metabolism (putative)
- release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate
Cofactor: binds 1 Zn+2 ion per subunit
Structure
- homooctamer (probable)
- belongs to the peptidase M18 family
Compartment
Expression
- ubiquitous
- upregulated with environmental enrichment in mice[2]
Notes
More general terms
References
- ↑ Taylor A. Aminopeptidases: structure and function. FASEB J. 1993 Feb 1;7(2):290-8. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8440407
- ↑ 2.0 2.1 Rampon C, Jiang CH, Dong H, Tang YP, Lockhart DJ, Schultz PG, Tsien JZ, Hu Y. Effects of environmental enrichment on gene expression in the brain. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12880-4. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11070096
- ↑ UniProt http://www.uniprot.org/uniprot/Q9ULA0.html