adiponectin receptor protein 2 (progestin & adipoQ receptor family member 2, ADIPOR2, PAQR2)

Function

• receptor for globular & full-length adiponectin
• role in metabolic pathways that regulate lipid metabolism, i.e. fatty acid oxidation
• mediates increased AMPK, PPARA ligand activity, fatty acid oxidation & glucose uptake by adiponectin

Structure

• may form homo & heteromultimers
• belongs to the ADIPOR family

Compartment

cell membrane & intracellular organelles

Expression

• expressed in skeletal muscle, liver , placenta > brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes, lung

More general terms

• transmembrane 7c protein
• progestin & adipoQ receptor (PAQR)

Additional terms

• adiponectin

Database

• OMIM: https://mirror.omim.org/entry/607946
• UniProt: http://www.uniprot.org/uniprot/Q86V24.html