folate receptor 2; folate receptor beta; FR-beta; folate receptor, fetal/placental; placental folate-binding protein; FBP (FOLR2)

Function

• binds to folate & reduced folic acid derivatives
• mediates delivery of 5-methyltetrahydrofolate to the interior of cells
• 8 disulfide bonds are present (probable)

Structure

• N-glycosylated
• belongs to the folate receptor family

Compartment

• cell membrane; lipid-anchor, GPI-anchor
• secreted (probable)

Expression

• expressed in placenta & hematopoietic cells
• expression is increased in malignant tissues

More general terms

• folate receptor or folate-binding protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2350
• OMIM: https://mirror.omim.org/entry/136425
• UniProt: http://www.uniprot.org/uniprot/P14207.html