KDEL receptor-2; ER lumen protein retaining receptor 2; KDEL endoplasmic reticulum protein retention receptor 2; ERD2-like protein 1; ELP-1 (KDELR2, ERD22)

Function

• required for retention of luminal endoplasmic reticulum proteins
• determines specificity of the luminal ER protein retention system
• also required for normal vesicular traffic through the Golgi
• receptor recognizes K-D-E-L (KDEL motif)

Structure

belongs to the ERD2 family

Compartment

endoplasmic reticulum membrane

More general terms

• KDEL receptor (ER lumen protein-retaining receptor)

Additional terms

• endoplasmic reticulum (ER)

Database

• OMIM: https://mirror.omim.org/entry/609024
• UniProt: http://www.uniprot.org/uniprot/P33947.html