retinoic acid early transcript 1G protein (RAET1G)

Function

• ligand for the NKG2D receptor
• mediates NK cell cytotoxicity
• binds to KLRK1/NKG2D & CMV glycoprotein UL16

Structure

belongs to the MHC class 1 family

Compartment

cell membrane

Alternative splicing

named isoforms=2

Expression

highly expressed in colon

Pathology

• high expressed in a number of tumor cell lines

More general terms

• cell surface receptor

Database

• UniProt: http://www.uniprot.org/uniprot/Q6H3X3.html