Rho GTPase-activating protein 18 (MacGAP, ARHGAP18)

Function

• GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state
• interacts with MPHOSPH6

Structure

contains 1 Rho-GAP domain

Alternative splicing

named isoforms=2

More general terms

• rho GTPase-activating protein (rho-GAP)

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N392.html