striatin-3; cell cycle autoantigen SG2NA; S/G2 antigen (STRN3, GS2NA, SG2NA)

Function

• binds calmodulin in a Ca+2 dependent manner
• may function as scaffolding or signaling protein
• interacts with protein phosphatase 2A (PP2A) (putative)

Structure

• belongs to the WD repeat striatin family
• contains 6 WD repeats

Compartment

• cytoplasm (putative), membrane
• peripheral membrane protein (putative)

Alternative splicing

• named isoforms=2; alpha, beta
• additional isoforms seem to exist

Notes

• originally thought to be nuclear

More general terms

• striatin family protein
• WD repeat protein family
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29966
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29966
• UniProt: http://www.uniprot.org/uniprot/Q13033.html