mesogenin-1 (MSGN1)

Function

• role in the formation & segmentation of paraxial mesoderm
• regulatory capacity to specify ventrolateral (including future paraxial), but not dorsal (future axial), mesoderm phenotypes
• seems to be an upstream regulator of at least some elements of the notch & delta signaling pathway

Structure

contains 1 basic helix-loop-helix (bHLH) domain

Compartment

nucleus (putative)

More general terms

• basic helix loop helix (bHLH) family transcription factor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3439
• UniProt: http://www.uniprot.org/uniprot/A6NI15.html