major facilitator superfamily domain-containing protein 8 (ceroid-lipofuscinosis neuronal protein 7, MFSD8, CLN7)

Function

• may be a carrier that transport small solutes by using chemiosmotic ion gradients (putative)

Structure

belongs to the MFS family

Compartment

lysosome membrane

Expression

expressed at very low levels in all tissues tested

Pathology

• defects in MFSD8 are the cause of neuronal ceroid lipofuscinosis type 7

More general terms

• transmembrane 12 protein
• major facilitator superfamily (MFS)

Database

• UniProt: http://www.uniprot.org/uniprot/Q8NHS3.html