phospholipid-transporting ATPase 2B; ATPase class 2 type 9B (ATP9B, ATPIIB, NEO1L, HUSSY-20)

Function

• role in the transport of phospholipids from the outer to the inner leaflet of various membranes & the maintenance of asymmetric distribution of phospholipids

ATP + H2O + phospholipid(In) = ADP + phosphate + phospholipid(out)

Structure

• belongs to the cation transport ATPase (P-type) (TC 3.A.3) family, type IV subfamily

Compartment

membrane

Alternative splicing

named isoforms=2

Notes

• uncertain whether Met-1 or Met-53 is the initiator

More general terms

• phospholipid-transporting ATPase

Additional terms

• HUSSY protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=374868
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:374868
• UniProt: http://www.uniprot.org/uniprot/O43861.html