phosphatidylinositol transfer protein beta isoform; Ptdins transfer protein beta; PtdinsTP; PI-TP-beta (PITPNB)

Function

• catalyzes transfer of Ptdins & phosphatidylcholine between membranes
• constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting

Structure

• belongs to the Ptdins transfer protein family, class I subfamily

Compartment

• cytoplasm (putative), Golgi apparatus

Alternative splicing

named isoforms=2

Expression

• widely expressed in various tissues including brain

More general terms

• phosphatidylinositol [PI] transfer protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23760
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23760
• OMIM: https://mirror.omim.org/entry/606876
• UniProt: http://www.uniprot.org/uniprot/P48739.html