ubiquitin-conjugating enzyme E2 E2; UbcH8; ubiquitin carrier protein E2; ubiquitin-protein ligase E2 (UBE2E2, UBCH8)

Function

• accepts ubiquitin from the E1 complex & catalyzes its covalent attachment to other proteins
• in vitro catalyzes Lys-11- & Lys-48-, as well as Lys-63-linked polyubiquitination
• protein modification; protein ubiquitination

Structure

• belongs to the ubiquitin-conjugating enzyme family

More general terms

• ubiquitin-conjugating protein E2 (ubiquitin carrier protein)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7325
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7325
• OMIM: https://mirror.omim.org/entry/602163
• UniProt: http://www.uniprot.org/uniprot/Q96LR5.html