ubiquitin-conjugating enzyme E2 J2; non-canonical ubiquitin-conjugating enzyme 2; NCUBE-2 (UBE2J2, NCUBE2)

Function

• catalyzes the covalent attachment of ubiquitin to other proteins
• seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD)
• protein modification; protein ubiquitination

Structure

• belongs to the ubiquitin-conjugating enzyme family

Compartment

• endoplasmic reticulum membrane
• single-pass type IV membrane protein (putative)

Alternative splicing

named isoforms=2

More general terms

• ubiquitin-conjugating protein E2 (ubiquitin carrier protein)
• membrane protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=118424
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:118424
• UniProt: http://www.uniprot.org/uniprot/Q8N2K1.html