cyclophilin C; peptidyl-prolyl cis-trans isomerase C

Function

• PPIases accelerate the folding of proteins
• catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
• cyclosporin A (CsA) inhibits CYPC

peptidylproline (omega=180) <--> peptidylproline (omega=0)

Structure

• belongs to the cyclophilin-type PPIase family
• contains 1 PPIase cyclophilin-type domain

Compartment

cytoplasm

More general terms

• cyclophilin
• chaperonin; chaperone

Database

• UniProt: http://www.uniprot.org/uniprot/P45877.html
• OMIM: https://mirror.omim.org/entry/123842
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5480