trypsin-6 (trypsinogen C, TRY6, T6)

Function

• preferential cleavage: Arg-|-Xaa, Lys-|-Xaa

Structure

• belongs to the peptidase S1 family, tryptase subfamily
• contains 1 peptidase S1 domain

Compartment

secreted (putative)

Expression

• overexpressed in metastasing in non-small-cell lung cancer, leading to an enhanced cell migration

Genetics

• could be the product of a pseudogene
• although being similar to trypsinogen, it appears to be a transcribed pseudogene

More general terms

• Ca+2 binding protein
• trypsin

Database

• UniProt: http://www.uniprot.org/uniprot/Q8NHM4.html