EF-hand domain-containing family member A1; Ca+2 uptake protein 2, mitochondrial (EFHA1, MICU2)

Function

• role in mitochondrial uniporter-mediated Ca+2 uptake
• probable regulator of the mitochondrial Ca+2 uniporter (MCU) (putative)
• component of a complex, at least composed of MCU, MICU1 & MICU2 (putative)

Structure

• contains 4 EF-hand domains

Compartment

mitochondria (putative)

Notes

• uncertain if this protein binds Ca+2 as none of the 4 EF-hand domains seem to contain a canonical Ca+2-binding site

More general terms

• Ca+2 binding protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IYU8.html