integrin alpha-7/beta-1
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Function
- primary laminin receptor on skeletal myoblasts & adult myofibers
- during myogenic differentiation, it may induce changes in the shape & mobility of myoblasts, & facilitate their localization at laminin-rich sites of secondary fiber formation
- involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability & functional integrity
Structure
- subunits: integrin alpha-7, integrin beta-1
Compartment
membrane