annexin A7; annexin-7; annexin VII; synexin (ANXA7, ANX7, SNX, OK/SW-cl95)

Function

• Ca+2/phospholipid-binding protein
• promotes membrane fusion
• is involved in exocytosis

Structure

• a pair of annexin repeats may form one binding site for Ca+2 & phospholipid
• belongs to the annexin family
• contains 4 annexin repeats

Alternative splicing

named isoforms=2

Expression

• isoform 1 is expressed in brain, heart & skeletal muscle
• isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts & placenta

More general terms

• annexin

Database

• UniProt: http://www.uniprot.org/uniprot/P20073.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=310
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:310
• OMIM: https://mirror.omim.org/entry/186360