calpain-13 (CAPN13)

Function

• non-lysosomal thiol-protease
• unlikely that calpain-13 binds Ca+2

Structure

• belongs to the peptidase C2 family
• contains 1 calpain catalytic domain
• contains 2 EF-hand domains.
  • unlikely that calpain-13 binds Ca+2 as neither of the 2 EF-hand domains contain a canonical Ca+2-binding site

Alternative splicing

named isoforms=2

Expression

• weakly expressed in lung & testis
• weakly or not expressed in other tissues

More general terms

• calpain

Database

• UniProt: http://www.uniprot.org/uniprot/Q6MZZ7.html