mannose-6-phosphate receptor-binding protein 1; cargo selection protein TIP47; 47 kD mannose 6-phosphate receptor-binding protein; 47 kD MPR-binding protein; placental protein 17 (PP17, M6PRBP1, TIP47, PLIN3)

Function

• transport of mannose 6-phosphate receptors from endosomes to trans-Golgi network
• interacts with the cytoplasmic domains of both M6PR & IGF2R

Structure

• homo-oligomer
• isoform A also exists as a homodimer (known as PP17C)

Compartment

• cytoplasm
• endosome: membrane associated on endosomes
• detected in envelope & core of lipid bodies & in lipid sails

Alternative splicing

named isoforms=2

More general terms

• oligomerizing protein
• placental protein
• perilipin; lipid droplet-associated protein (PLIN)

More specific terms

• mannose 6 phosphate receptor binding protein 1 isoform a

Database

• OMIM: https://mirror.omim.org/entry/602702
• UniProt: http://www.uniprot.org/uniprot/O60664.html