apolipoprotein A2 (APOA2)
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Function
- structural protein of HDL
- function of apo A2 is not entirely clear; however, it appears to play a play a stuctural role in HDL & a role in activation of triglyceride lipase & inhibition of LCAT
- Met-49 is oxidized to methionine sulfoxide
- phosphorylation sites are present in plasma
- forms a disulfide- linked heterodimer with APOD
- interacts with HCV core protein
- interacts with APOA1BP & NDRG1
Structure
- homodimer, disulfide-linked
- belongs to the apolipoprotein A2 family
Compartment
Expression
More general terms
References
- ↑ Primary Hyperlipoproteinemias, Steiner & Shafrir (eds), McGraw Hill, NY, 1991, pg 24
- ↑ Tietz Textbook of Clinical Chemistry, 2nd ed. Burtis CA & Ashwood ER (eds), WB Saunders Co, Philadelphia PA, 1993, pg 1021
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=336
- ↑ UniProt http://www.uniprot.org/uniprot/P02652.html
- ↑ SHMPD; Singapore human mutation and polymorphism database http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=APOA2