cytochrome b-c1 complex subunit 1, mitochondrial; complex III subunit 1; core protein I; ubiquinol-cytochrome-c reductase complex core protein 1; process-enhancing protein (UQCRC1)

Function

• component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), a component of the mitochondrial respiratory chain
• may mediate formation of the complex between cytochrome c & cytochrome c1
• UQCRC1 is a subunit of both ubiquinol-cytochrome c reductase & mitochondrial processing peptidase
• does not seem to have a protease activity as it lack the Zn+2-binding site

Structure

• belongs to the peptidase M16 family, UQCRC1/QCR1 subfamily

Compartment

• mitochondrial inner membrane

Comparative biology

• MAS1/MIF1 in fungi

More general terms

• protein subunit
• chaperonin; chaperone
• mitochondrial membrane protein
• phosphoprotein

Component of

• ubiquinol cytochrome c reductase; respiratory complex 3
• mitochondrial-processing peptidase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7384
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7384
• OMIM: https://mirror.omim.org/entry/191328
• UniProt: http://www.uniprot.org/uniprot/P31930.html