NADH dehydrogenase subunit-4L (MT-ND4L)

Function

• subunit of NADH dehydrogenase (mitochondrial complex 1)

NADH + ubiquinone <--> NAD+ + ubiquinol

Compartment

mitochondrial inner membrane

Pathology

• defects in MT-ND4L are a cause of Leber hereditary optic neuropathy

More general terms

• NADH dehydrogenase subunit
• flavoprotein

Component of

• NADH dehydrogenase; respiratory chain complex-I; NADH CoQ reductase;NADH-ubiquinone oxidoreductase

Database

• UniProt: http://www.uniprot.org/uniprot/P03901.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4539
• OMIM: https://mirror.omim.org/entry/516004
• OMIM: https://mirror.omim.org/entry/535000