P2X1 purinoceptor; ligand-gated ion channel purinergic receptor P2X1; P2X purinoceptor 1 P2X1 (P2RX1, P2X1)
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Function
- ligand-gated ion channel with high Ca+2 permeability
- binding of ATP mediates
- synaptic transmission between neurons
- transmission from neurons to smooth muscle
- may be linked to apoptosis via increasing intracellular Ca+2
Structure
Compartment
membrane
Pathology
- defects in P2RX1 are a cause of bleeding disorder(s)
More general terms
References
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5023
- ↑ UniProt http://www.uniprot.org/uniprot/P51575.html
- ↑ Wikipedia; Note: P2X receptor entry http://en.wikipedia.org/wiki/P2X_receptor
Wikipedia; Note: P2RX1 entry http://en.wikipedia.org/wiki/P2RX1