K+ channel subfamily K member 16; TWIK-related alkaline pH-activated K+ channel 1; 2P domain K+ channel Talk-1 (KCNK16 TALK1)

Function

• outwardly-rectifying K+ channel
• produces rapidly activating & non-inactivating outward rectifier K+ currents

Structure

• homodimer (putative)
• belongs to the two pore domain K+ channel (TC 1.A.1.8) family

Compartment

membrane

Expression

• highly expressed in pancreas
• not detectable in the other tissues tested

Notes

• inhibited by Ba+2, quinine, quinidine, chloroform & halothane
• activated at alkaline pH

More general terms

• K+ channel subfamily K
• transmembrane 4 protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=83795
• OMIM: https://mirror.omim.org/entry/607369
• UniProt: http://www.uniprot.org/uniprot/Q96T55.html