cytochrome P450 4V2 (CYP4V2)

Function

• unknown
• may have a role in fatty acid & steroid metabolism

Structure

belongs to the cytochrome P450 family

Compartment

endoplasmic reticulum membrane

Alternative splicing

named isoforms=2

Expression

• broadly expressed
• detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, retina, retinal pigment epithelium & lymphocytes

Pathology

• defects in CYP4V2 are a cause of Bietti crystalline corneoretinal dystrophy

More general terms

• cytochrome P450

Database

• OMIM: https://mirror.omim.org/entry/608614
• OMIM: https://mirror.omim.org/entry/210370
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2854
• UniProt: http://www.uniprot.org/uniprot/Q6ZWL3.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=285440