glucosamine-6-phosphate isomerase 1; glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; oscillin (GNPDA1, GNPI, HLN, KIAA0060)

Function

• seems to trigger Ca+2 oscillations in mammalian eggs
• these oscillations serve as the essential trigger for egg activation & early development of the embryo (putative)

D-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3

Structure

• homohexamer
• belongs to the glucosamine/galactosamine-6-phosphate isomerase family

Compartment

cytoplasm (putative)

More general terms

• isomerase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10007
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10007
• OMIM: https://mirror.omim.org/entry/601798
• UniProt: http://www.uniprot.org/uniprot/P46926.html