L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; 4'-phosphopantetheinyl transferase; alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; AASD-PPT; LYS5 ortholog (AASDHPPT)
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Function
- catalyzes the post-translational modification of target proteins by phosphopantetheine
- transfers 4'-phosphopantetheine moiety from coenzyme A to Ser of phosphoproteins, including acyl carrier domain of FASN
Structure
- monomer
- belongs to the P-Pant transferase superfamily, AcpS family
Compartment
Expression
- expressed in heart, skeletal muscle, placenta, testis, brain, pancreas, liver, kidney