otoancorin

Function

• adhesion receptor

Structure

• belongs to the stereocilin family

Compartment

• apical cell membrane, GPI-anchor, extracellular side
• interface between apical surface of epithelia & overlying acellular gel of tectorial otoconial membranes

Alternative splicing

named isoforms=3

Pathology

• defects in OTOA are a cause of autosomal recessive non-syndromic sensorineural deafness type 22

More general terms

• adhesion receptor
• glypiated protein

Database

• OMIM: https://mirror.omim.org/entry/607038
• OMIM: https://mirror.omim.org/entry/607039
• UniProt: http://www.uniprot.org/uniprot/Q7RTW8.html